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If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy

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In vitro studies use concentrations of 1-10 micromolar

However, chronic users of non-steroidal anti- inflammatory drugs (NSAIDs) have an increased risk of bleeding and visible damage to their small intestine (28)

Effects of near-infrared light on well-being and health in human subjects with mild sleep-related complaints: A double-blind, randomized, placebo-controlled study

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